Everything about ceesdekker.net
Everything about ceesdekker.net
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‘Sure, that is definitely about correct. I seek for a physical knowledge of Organic methods inside of a base-up way. I think you can distinguish a few lines of exploration in my group in the intervening time. The very first problems chromosome structure: How would you get a metre-extended DNA polymer folded and organised in this type of microscopic mobile? We have produced visualisation approaches that allow us to study how, one example is, SMC proteins loop DNA (online video on Youtube) to be able to Construct up chromosomes.
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, Groningen researchers current the outcome in their initiatives for making labs extra sustainable and provide techniques for other labs.
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
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Microbiology has only been around to get a century, given that we began to review micro-organisms additional very seriously. I assumed nanobiology was an appropriate term, simply because all molecular biological pertinent interactions take place on the nanoscale: a protein is several nanometres in measurement, DNA is 2 nm thick.’
Quite a few similar developments adopted, where by our team founded distinctive transistor variants such as single-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled a number of transistors into compact evidence-of-basic principle Digital circuits.
Finding out DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule ceesdekker.net assays.
‘Sure, I have an understanding of folks were being shocked at enough time. At the end of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I've to admit that it experienced turn into a bit bored, I didn’t understand much any more. The sector went extra into the application aspect, how you could potentially integrate nanotubes into electronic circuits.
Resolving the action dimensions in condensin-driven DNA loop extrusion identifies ATP binding since the phase-creating method
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
2006, to start with demonstration of molecular sorting within a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and initially estimate of electrokinetic energy conversion in a nanofluidic channel
Let’s initial search back again in the meanwhile after you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
The biophysicist from Delft – who has been one of the most cited experts from the Netherlands For several years – normally takes his duty to contribute into the rationalization and popularisation of his operate on the border of physics and biology very seriously and consistently seems inside the media; if not to look at his operate, then about the relationship concerning science and his Christian religion.